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Senior R&D Engineer - Microfluidics

Bay Area, CA

Senior R&D Engineer - Microfluidics

Prellis Biologics employs 2-photon holography to print human tissues and organs in real time. Current applications of our platform include printing of lymph node organoids, which we are using to generate in vitro human antibody libraries, camelid antibody libraries, in vitro human immunogenicity screening, human primary tumor/lymph node co-cultures for therapeutic screening, and vaccine R&D. Prellis’ ability to print and culture healthy human tissue provides it with unique opportunities for generating and screening next generation human therapeutics.

Prellis Biologics is seeking a Senior R&D Engineer, Microfluidics to drive the research and development of next-generation human tissue development. This role requires microfluidics and chip-to-world interface experience. The ideal candidate is comfortable working in the lab, collaborating with cell biologists, and enjoys solving complex problems.

Key Responsibilities:

  • Design, build, and test microfluidic chip-to-world systems, such as interface bonding between different materials, development of cartridges, and integration of valves and pumps

  • Perform microfluidic and system calculations and simulations to inform design and test

  • Execute on microfluidic and systems CAD drawing

  • Integration of components such as microfluidics, soft material 3D scaffolds, fluidic systems, and cell biology

  • Keep rigorous documentation

  • Maintain up-to-date design rules

  • Collaborate with Biology and Engineering teams to test and troubleshoot problems

  • Basic cell biology assays including cell viability and simple imaging experiments

  • Ownership of failure analysis and development of metrology methods

  • Contribute to the generation of intellectual property

Skills and Experience:

  • Ph.D. in Mechanical Engineering, Biomedical Engineering or a related discipline. An excellent publication record is a strong plus

  • 4+ years of hands-on experience designing and developing microfluidics and microfluidic systems for life sciences

  • Fundamental understanding of microfluidic flow and transport phenomenon

  • Experience with mammalian cell culture and sterility techniques, familiarity with basic molecular and cell biology

  • Experience with Tissue Engineering techniques

  • CAD software experience

  • Data-driven, proficient with design of experiments (DOE) and statistical analysis

  • Ability to communicate results, ideas, problems, and solutions to experts and non-experts within an interdisciplinary environment

Please send your resume to to apply.

Prellis is committed to the principles of equal employment opportunity. Applicants are considered for all positions without regard to race, sex, sexual orientation, color, religion, national origin, age, and disability (so long as such disability can be reasonably accommodated) or any other status protected by applicable law. Prellis encourages all qualified applicants to apply.