We mentioned that our tech is revolutionary, but
Take our customers' word for it
Marcus Muench, PhD
Associate Adjunct Professor
When you have complexity, like in [conventional] organoids or in animals – you increase variability. So we think we can reduce variability using the [Prellis] organoids especially going from the organoid to in vivo. The structures are also more consistent, so less variability from that perspective too. Less variability means quicker, with less cost and more tests – to results.
Maria Soloveychik, PhD
We were using a few grow your own spheroid techniques. They required intricate setups and were not as consistent in size and morphology, complicating downstream analysis. What changes with Prellis – you just use it. The setup is quick and consistent, and the handling is straightforward. There is a little pain, as in most cases, but a lot less than before. 100% better.
Michael Jones, PhD
Cell Guidance Systems
3D cell culture is a rapidly developing field with significant commercial and scientific importance. Prellis Bio’s ability to print micro-scale 3D structures, such as detailed vasculature, quickly and at reasonable cost is impressive. Their technology provides a radical new dimension in our ability to control cell behaviour by tightly manipulating and controlling micro-scale architecture of 3D culture.
Jennifer Erwin, PhD
Johns Hopkins University
The issue of vascularization of the organoid models is key. The traditional organoids are not healthy, because they have no vasculature, which is what gets nutrients through the structure. Really it is the tissue, just cells piled on to each other [and] in the center of that pile they have no nutrients, no oxygen – and they die. So the idea is that the Prellis structure, with the vasculature, keeps it from dying.
San Jose State University
We have been using Prellis since early March. What’s changed? We tried to do 3D on our own. Difference with Prellis is the size. Their size is a lot larger than ours. And the speed. Our cultures took significant time – 10 – 12 days or more, while Prellis is a 24 hour seed cycle to get started with your experiment. Plus, the ease of the technique is important, because you can pass the technique from one person to another with very little training. It allows you to start right away on the important research – we could start 24 hours after putting the cells in scaffolding.
Holger Russ, PhD
University of Colorado - Denver
Cells exist in 3D – so they don’t function well in 2D. So when it is 3D like a human, it can function more like a normal cell would...if we take a 3D organized structure into pre-clinical models we get the survival advantage... We see Prellis bringing that to us...So that Prellis can customize and provide the resolution of structures like they do, no one can do that to our knowledge. Not to the accuracy and scale. I’m doing this for 12 years. I’m on scientific advisory boards. I know what’s out there. So I know this is the case.