Scientist, Immunology / Immuno-Oncology

Bay Area, CA

Prellis Biologics employs 2-photon holography to print human tissues and organs in real time. Current applications of our platform include printing of lymph node organoids, which we are using to generate in vitro human antibody libraries, camelid antibody libraries, in vitro human immunogenicity screening, human primary tumor/lymph node co-cultures for therapeutic screening, and vaccine R&D. Prellis’ ability to print and culture healthy human tissue provides it with unique opportunities for generating and screening next generation human therapeutics.


We are looking for a highly motivated Immunologist/Immuno-Oncologist to make critical contributions to our growing in vitro tumor model platform. The individual will be part of a dynamic and integrated research team focused on supporting multiple aspects of a therapeutic drug discovery and validation pipeline. 


Essential Functions


In Prellis’ fast-paced, small business environment, the successful candidate will:


  • Develop and execute in vitro assays in support of 3D tumor model development

  • Possess excellent expertise in immune profiling of immune cells and components of the tumor microenvironment via multi-panel flow cytometry

  • Make strong intellectual contributions to tumor model engineering and in vitro immune process development

  • Perform high resolution imaging of the 3D tumor immune models via fluorescence and confocal microscopy

  • Execute assays for the characterization of candidate therapeutics

  • Interact effectively with scientists, engineers, and clients from different disciplines

  • Analyze and present research findings at scientific team meetings


This description has been designed to indicate the general nature and level of work performed by the sought employee. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities, and qualifications required of employees assigned to this job.


Preferred Experience and Education


The successful candidate is an immunologist who:


  • Has a Ph.D. in immunology / immune-oncology or relevant field with at least 2 years of industry experience

  • Has prior experience working with primary human immune cells and their isolation from tissue

  • Has familiarity with therapeutic development pipelines


Required Skills


  • Deep knowledge of immunology (cells, signaling, and pathways) and oncology

  • Proficiency in:

  • Primary cell isolation and culture

  • Multi-color flow cytometry and analysis

  • Fluorescence microscopy and image analysis

  • Large dataset analysis

  • Strong experimental design skills

  • Attention to detail

  • Strong communication and data presentation skills

  • Strong collaboration, organizational, time management, and problem-solving skills


Preferred Additional Skills


  • Knowledge of cancer biology and systems immunology

  • Project management skills

  • Proficiency in:

  • Bioinformatic analysis of proteins and sequences

  • Molecular biology techniques

  • Laboratory systems development and implementation

  • Softwares: FlowJo, GraphPad Prism, Google Suite

  • Ability to work independently and in a cross-functional team environment

  • Strong writing/presenting skills


Other Requirements


Candidates should be:

  • Able to relocate to the Bay Area as needed

  • Enthusiastically willing to work in lab 80-90% of the time


Please send your resume to careers@prellisbio.com to apply.


Prellis is committed to the principles of equal employment opportunity. Applicants are considered for all positions without regard to race, sex, sexual orientation, color, religion, national origin, age, and disability (so long as such disability can be reasonably accommodated) or any other status protected by applicable law. Prellis encourages all qualified applicants to apply.